BRMS 1 ( breast cancer metastasis suppressor 1 )
نویسندگان
چکیده
BRMS1 is a functioning gene comprising 10 exons and spanning 7.8 kb of genomic DNA. Alternative splicing results in two mRNA transcripts, translating into two distinct proteins, 246 amino acids and 290 amino acids in length, respectively (Seraj et al., 2000). The longer transcript uses an alternative splice site in the 3' untranslated terminal exon which results in the use of a downstream stop codon. The encoded protein has a longer distinct C-terminus. Transcription
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